MEDICINAL CANNABIS cultivation facilities (GMP) | CarbonActive
Swiss Facility Solutions

Cultivation solutions for medicinal cannabis

Pharma-grade quality, documented purity, reproducible climate. CarbonActive supplies GMP-compliant indoor facilities with HEPA filter cascade, pressure cascades between cleanroom zones and four-pipe air conditioning technology - for validatable pharmaceutical output.

H13 HEPA filter stage in the supply air
±0.5 K Temperature tolerance
ISO 7/8 Clean room class validatable
Interior view of a CarbonActive Indoor Growing Compartment for medicinal cannabis cultivation according to GMP standards with cleanroom-compatible LED lighting and filter cascade
Filter cascade
F7 → F9 → H13
Climate stability
±0.5 K - ±3 % rH

How many patients per IGC?

Before we talk about GMP cleanroom technology - the most important figure first: how many patients you can supply reliably and in pharmaceutical quality with a single Indoor Growing Compartment .

1 IGC
275 PATIENTS

at 25 g / month

2 IGCs
550 Patients

at 25 g / month

3 IGCs
825 PATIENTS

at 25 g / month

Assumptions: 500 g/m² yield - 4.7 passes per year - 36 m² net cultivation area per IGC

From the recipe to your own facility

The German market for medicinal cannabis is growing exponentially - and the supply gap between prescriptions and pharma-grade production is large. Those who build now will secure pharmacy supply contracts.

2017

MEDICINAL CANNABIS as medicine

Prescription capability introduced - start of the German pharmaceutical cannabis market

Apr 2024

BtM deletion

Cannabis out of the BtMVV - simplified prescription, explosive growth in demand

2025

Supply gap

Import dependency as a risk - pharmacies are looking for reliable EU GMP suppliers

Now

Secure market share

GMP-compliant local production displaces imports and secures long-lasting pharmacy contracts

Indoor Growing Compartments

GMP compliance requires reproducible conditions. The IGC is CarbonActive's answer to this: a pre-configured cultivation room's with the same yield in two climate variants - you choose whether or not you need daytime operation, even in midsummer .

IGC Basic

Seasonally optimal
  • Energy recovery for passive cooling & dehumidification
  • Optimum climate for approx. 70 % of the year without aids
  • In midsummer: light phase at night, dark phase during the day
  • Integrated active CO₂ fumigation
  • 4 walls, lateral ventilation, height-adjustable lighting
  • 36 m² net cultivation area (50-60 m² gross)
  • Upgrade to Professional possible at any time
Arrange a consultation
When exactly will Basic reach its barriers? In Germany, conditions of over 30 °C and more than 60 % relative humidity occur at the same time . air humidity typically under 50 hours a year. If you can switch to night light phases during this time , you can get away with Basic all year round. If you want to work at any time during the day and maintain the target climate exactly even on humid summer days, choose Professional.

Custom Facilities

For projects with 4 IGCs or more (144m² net cultivation area), it is worth planning a customized facility with an optimized climate control system.

  • Highly efficient, fully integrated air conditioning system
  • Lower initial and ongoing costs per m²
  • Economies of scale through central components
  • Tailor-made for your building characteristics
Recommended from 144m²
Request individual advice
GMP compliance - Step 1

How the filter cascade works

In a GMP-compliant facility, outside air is not introduced directly - it passes through a multi-stage cleaning cascade. Each variant removes finer particles before the air enters the GMP zone. The result: HEPA filtration at HEPA level, documented and validatable.

AUSSEN- LUFT unbehandelt F7 VORFILTER ePM2.5 ≥ 65 % grobe Partikel · Pollen F9 FEINFILTER ePM1 ≥ 80 % Sub­mikron · Aerosole H13 · HEPA SCHWEBSTOFF ≥ 99,95 % @ MPPS Bakterien · Viren GMP-ZONE Verpackung · Produktion VERPACKUNGS­LINIE Δp +30 Pa · ISO 8 ÜBERDRUCK +30 Pa CARBONACTIVE · STEUERUNG ●Δp · Volumenstrom · Filterüberwachung
F7Pre-filter- coarse particles - ePM2.5 ≥ 65 %
F9Fine filter- submicron - ePM1 ≥ 80 %
H13HEPA- Suspended particulate > 99.95 % @ MPPS
GMP compliance - Step 2

From corridor to cleanroom

Filters alone are not enough. A GMP cleanroom also needs a controlled pressure cascade: each zone has a higher pressure than the adjacent, less clean zone - so that air flows out of the cleanroom, never into it. Personnel and material airlocks function as pressure buffers.

The pressure values shown are exemplary - exact design parameters are defined on a project-specific basis.
AUSSEN / KORRIDOR 0 Pa PERSONAL­SCHLEUSE +15 Pa Eingangs­zone F7-Filterstufe GMP-KLASSE D +30 Pa Verpackung Vor­stufe · ≈ ISO 8 F7 + F9 max. 3.520.000 /m³ Partikel ≥ 0,5 µm · in Ruhe GMP-KLASSE C +45 Pa Produktion · Verpackung · ≈ ISO 7 F7 + F9 + H13 max. 352.000 /m³ Partikel ≥ 0,5 µm · in Ruhe REINSTLUFT Δp = 0 Δp = +45 Pa · GMP Klasse C
01 / Print
0 → +45 Pa

Four-variant cascade from corridor to GMP zone - air flows in one direction only.

02 / Purity
99.95 % @ MPPS

Filter combination F7 - F9 - H13 - validatable according to EU GMP classes C/D (ISO 7 / ISO 8).

GMP compliance - Step 3

The four-pipe system: constant climate without fluctuations

Pharmaceutical cannabis production requires reproducible conditions - no fluctuations, no drift. Our four-pipe system runs cold and hot water in parallel: while one heat exchanger cools, the next can reheat immediately. This keeps the climate stable within a range of ±0.5 K temperature and ±3 % relative air humidity - second by second.

23.0 22.5 22.0 21.5 21.0 TEMPERATUR · °C 0h 6h 12h 18h 24h ZEIT (24 STUNDEN) SOLLWERT +0.5 K TOLERANZ −0.5 K TOLERANZ IST-WERT KLIMA-STABILITÄT · 24h
01 / Temperature

±0.5 K Tolerance

Constant target value over 24 hours - no fluctuations that could disturb the active ingredient content or trichome formation.

22 °C Setpoint - stable
02 / Humidity

±3 % tolerance

Tightly regulated in the optimal VPD range - moist enough for healthy plants, dry enough against mold and botrytis.

60 %rH Setpoint - stable
What does this mean for you? Reproducible active ingredient profiles between batches, fewer rejects due to the risk of mold, documentable climate profiles for GMP validation - and therefore a facility that qualifies for pharmacy supply contracts and export.

Competitive advantage in Central Europe

What many overlook: Where the IGC is located determines how efficiently it runs. Central Europe's temperate climate is not a disadvantage for our technology - it is its greatest lever.

  • 8 months optimal conditions

    The cool, but not bitterly cold outside temperature in Germany is ideal for passive cooling and dehumidification.

  • Summer air humidity below 60%

    In contrast to other regions, air humidity remains moderate in the summer - ideal for open and SemiLoop ventilation systems.

  • SemiLoop technology

    Our hybrid system combines energy-saving climate control with the performance of closed systems.

Los Angeles, USA Summer too warm, too humid all year round
-808162432-20020406080Temperatur in °CRel. Luftfeuchtigkeit in %JanFebMärAprMaiJunJulAugSepOktNovDez
Toronto, Canada Winter too cold, LF too high
-808162432-20020406080Temperatur in °CRel. Luftfeuchtigkeit in %JanFebMärAprMaiJunJulAugSepOktNovDez
Bangkok, Thailand Unsuitable all year round
-808162432-20020406080Temperatur in °CRel. Luftfeuchtigkeit in %JanFebMärAprMaiJunJulAugSepOktNovDez
Berlin, Germany 8 months optimal, summer LF top
-808162432-20020406080Temperatur in °CRel. Luftfeuchtigkeit in %JanFebMärAprMaiJunJulAugSepOktNovDez
Average daily temperature in °C Rel. air humidity in % Optimum efficiency Energy Recovery Group

SemiLoop technology

Harnessing the climate advantage is the real engineering achievement . Three generations of climate control systems lead to our hybrid answer.

CarbonActive SemiLoop hybrid climate system - ventilation and heat exchanger technology for energy-efficient indoor cannabis cultivation
The SemiLoop system combines open and closed air conditioning technology in one facility.

Open systems

20 years ago

Moderate electricity prices, less sensitive genetics, NDL lighting as standard.

CLOSED SYSTEMS

Last 10 years

Development for higher quality requirements and LED technology.

Hybrid SemiLoop

CarbonActive Innovation

Combines energy-saving climate control with dehumidification performance of closed systems.

Electricity savings in comparison

Climate control electricity consumption in Central Europe

100%
Conventional Closed system
6-10× more efficient 10-17%
SemiLoop Hybrid technology
Up to 10× less electricity for climate control

How climate control works in the IGC

The diagram shows the complete air treatment process in an IGC realized : First, the Energy Recovery Group heat exchanger passively transfers the energy of the warm return air to the cold outside air. If this is not sufficient, the filter, cooling and reheater take over the active conditioning - until the supply air is exactly at setpoint. In this way, the climate in the cultivation room'S remains stable, with minimal energy consumption.

IGC · AHU-LÜFTUNGSSCHEMA offen + geschlossen kombiniert · ERG mit aktiver Konditionierung RÜCKKÜHLER KALT- WASSER WARM- WASSER AUSSEN- LUFT unbehandelt FORTLUFT abgekühlt AHU · AIR HANDLING UNIT ERG · KREUZ-WT Energierückgewinnung FILTER F7 · F9 · H13 VENTILATOR Druck · Volumenstrom KÜHLUNG + Entfeuchtung NACHWÄRMER auf Soll-Temperatur RÜCK- LUFT warm · feucht ZULUFT 22 °C · 65 %rH konditioniert IGC ANBAURAUM · CANNABIS 25 °C · 65 %rH · stabil · gleichmässig verteilt höhen- verstellb. NETBOW · TROPFBEWÄSSERUNG SEITENLÜFTUNG SEITENLÜFTUNG T/rH CARBONACTIVE ●STEUERUNG & SENSORIK
Outside air / exhaust air (cold - without energy)
Supply air preconditioned & return air (with energy)
Supply air conditioned (to setpoint)
Energy Recovery Group heat transfer (passive)
Plants - Drip irrigation

Energy-saving

Optimized use of outside air with 8 months of optimal conditions

Low fluctuation

Constant climate conditions for maximum yields

PLC-controlled

Precise control systems via sensors, control technology and control cabinet construction

Energy recovery

Up to 80% heat recovery from the exhaust air

Energy Recovery (ERG)

At the heart of every SemiLoop facility is a heat exchanger that recirculates the exhaust air energy. This is where most of the electricity savings are generated in open operation - and the basis for closed operation is laid.

HEAT EXCHANGER principle

More than 80% of the heat energy is transferred to the supply air when the exhaust air is discharged. No additional heating is required when the lighting is switched on.

Passive dehumidification

In cold, dry outside air, the system passively dehumidifies without additional power consumption.

Passive cooling

If the outside air is colder than in the cultivation room's, energy-efficient cooling takes place via the ventilation system.

Active heating

Only when the energy recovery reaches its barriers (e.g. winter when the lights are off) is the system actively reheated.

Energy recovery

80%+
Heat recovery 80%
Optimal season 8 months
Climate electricity savings 6-10×
IGC Professional Feature

Heating without electricity: the hot water tank

The Energy Recovery Group recovers the heat from the exhaust air - what happens to the heat that the active air conditioning system dissipates at the height of summer? With conventional closed systems, it is lost and must be replaced in the dark phase with electric heating coils . Twice the energy for the same cultivation room'S.

In the IGC Professional, we store this waste heat in a hot water tank and use it to reheat the room, when the lighting is switched off. This makes closed operation significantly more energy-efficient - and dehumidification without electrical reheating practical in the first place.

  • Waste heat from the climate control system is stored instead of dissipated
  • Dehumidification without separate electric heating
  • Closed operation as efficient as open systems
Conventionally closed
CLIMATE CONTROL SYSTEM cools
× Waste heat dissipated → lost
Heating coil needs electricity
vs.
IGC Professional
CLIMATE CONTROL SYSTEM cools
Waste heat → Hot water tank
Heating with stored energy

Technical components

Energy Recovery Group and hot water tank are just two components. Six components matched to each other turn your warehouse into a cultivation room's ready for production.

01

AHU - Air Handling Unit

The heart with pre-filter, energy recovery and activated carbon filter for odor-free operation.

  • Pre-filter for harmful particles
  • Activated carbon filter Odor protection
  • Integrated control systems
02

Lateral ventilation

Optimized ventilation via the sides for even air circulation without direct draughts on the plants.

  • 3 variants selectable
  • Electrically height-adjustable optional
  • Even air circulation
03

HEAT EXCHANGER

Highly efficient heat transfer between supply and exhaust air for maximum energy savings.

  • >80% heat recovery
  • Passive dehumidification
  • Integrated hot water tank
04

Control cabinets & BMS

Intelligent building control with modern PLC technology for precise climate control.

  • Modern PLC control systems
  • Sensors & control technology
  • Remote access possible
05

CO₂ fumigation

Integrated system for active CO₂ supply in the initial weeks during closed operation.

  • Integrated in all IGCs
  • Humidity maintenance
  • Healthy plant growth
06

Tables & lighting

Optimum use of space with movable benches and electrically height-adjustable lighting mounts.

  • 36m² net cultivation area
  • 900 or 1300 µmol/m²/s
  • Electrically height-adjustable

Lighting configuration

One of the few places where you actively configure: How much light should fall on your plants? There are three light levels to choose from - each with its own climate planning.

Beginner
4 Lamp rows

850 µmol/m²/s

Lower light intensity with moderate climate requirements. Ideal for beginner projects and cultivation that is gentle on the variety.

Maximum
6 Lamp rows

1150 µmol/m²/s

Maximum light intensity for maximum yields. Increased climate requirements - ideal for crop steering professionals.

Standard equipment in every IGC

Height-adjustable lighting Adapted to the growth phase at the touch of a button
Height-adjustable lateral ventilation Precise air flow directly at the plant basket
Integrated CO₂ fumigation Active supply in the initial weeks
Energy recovery Up to 80% heat recovery from the exhaust air

Room layout: many small vs. few large rooms

With the light intensity, you know how much will grow per square meter - now it's a question of how many rooms will fit in your warehouse. This decision influences risk, flexibility and costs.

Criterion Few large rooms Many small rooms
Loss risk Lower Lower
Variety of strains Limited High
Staff utilization More difficult Optimal
Response options Limited Flexible
Cost per m² Lower Higher
Ideal for areas From 144m² (4 rooms) Less than 144m²

Our recommendation

36m² net cultivation area per room is the sweet spot - lots of small but not too expensive rooms. From 144m² 4 rooms are recommended, from 288m² already 8 rooms.

Profitability & return on investment

You now know the system, the configuration and the rooms - the question remains: What does it cost and when does it pay off?

Optimal climate throughout the year
Share of cultivation schedule without climate adjustments
Basic - 70 %
Professional - 100 %
Daytime operation also possible in midsummer

When will your facility pay for itself?

Medicinal cannabis has two advantages over the consumer market: pharmaceutical-grade margins are higher, and pharmacy supply contracts are long-lasting. In a scenario with 500 patients, 25 g monthly supply and a pharmacy price starting at €8/g, an IGC facility typically pays for itself within 12 months - the GMP requirements for the clean room and filter cascade are already included.

Scenario: 500 patients

With 25 g purchase/month and pharmacy margins

Pharma grade margins

Higher retail prices than consumer cannabis due to GMP certification

Long-lasting contracts

Pharmacy supply instead of spot market - calculable purchase over years

Discuss profitability

From planning to the first harvest

Once the economic viability has been established, things become concrete: six phases lead from the first meeting to commissioning. With IGC facilities much faster than with custom facilities.

01

Concept development

Required cultivation area, cultivation method, climate conditions, planning Adjoining rooms

2-6 weeks
02

Rough planning

On-site visit incl. measurements, cost estimate, finalization Room layout

2 days
03

Detailed planning

Preparation of building applications, identification of suppliers, finalization Building planning

2-3 days
04

Manufacturing

Planning delivery deadlines, in-house production, determine final budget

8-12 weeks
05

Installation

Construction measures, BMS programming, final building acceptance

1 week per IGC
06

Commissioning

Handover to customers, training systems, cleaning & maintenance plan

1 day

IGC facility: Standardized design, less planning effort - if conversion approval is available, the facility can initially be built to variant Basic and later upgraded to Professional.

CUSTOMOM FACILITY: Customized climate planning with fully integrated system - longer planning phases, but lower initial and operational costs per m² from 4 IGCs (144 m²).

GMP ventilation system realized by CarbonActive at Pure Pharma in Laufenburg
Reference project

GMP ventilation in practice: Pure Pharma

How CarbonActive implemented a GMP-compliant ventilation system for Pure Pharma in Laufenburg - Filter cascades, pressure cascades and reproducible clean room climate for pharmaceutical production. Take a look at the project in detail .

To the reference page

Ready for pharma-grade cannabis?

We support you from the cleanroom concept to GMP validation. Let us discuss the right filter cascade, pressure cascade and climate design for your project - free of charge and without obligation.

Free initial consultation Swiss quality EU GMP-compliant planning
FI3A6746-3_frei

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Together we realize your cultivation project

Book an appointment with our expert Lorenz Minks as soon as possible.

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